I did not write this but its very interesting information that should be shared! It came from the University of Michigan sports blog. Lot of smart Doctor types that hang out there.
C****-** Asymptomatic - Not what you may think
Submitted by Aspyr on June 22nd, 2020 at 8:04 AM
Caveat: There is a lot yet to learn about C****-** and I am not an expert in infectious disease. That said just a couple of months ago most experts were saying that face masks weren't that important for the general public and there was no ability to spread if you didn't have a fever.
C****-** Asymptomatic - Not what you may think
One thing that I have been curious about is why the Spanish flu of 1918 was so deadly to young and younger adults and in comparison the same group seems to be spared with C****-**.
First, being asymptomatic to a v***s does not mean that you fought the v***s off and your body did so a great job that you had no symptoms - on the contrary - it means that your i****e s****m does not recognize the v***s and didn't fight it in the first place. Experts believe this is very rare in regards to v***ses and especially to the percentage of people with C****-** that are asymptomatic. Which possibly means that there is something new enough about this v***s that most younger people have not already been exposed but also means that older people have been exposed to a similar v***s in the past.
As can be imagined most people being examined are those with symptoms but now studies and reports are coming out that show what affect this v***s is having on asymptomatic carriers.
Here are some of those findings:
1) Those that are asymptomatic have similar if not more of the v***s than those that show symptoms. They have known this for a while.
2) Asymptomatic carriers shed the v***s longer that those that show symptoms. Those with mild symptoms shed the v***s less that those with more severe responses.
Average v***l shedding after infection
Asymptomatic - 19 days
With Symptoms - 14 days
3) Those with symptoms have a higher count of v***s antibodies after recovery than asymptomatic carriers. In fact it appears that asymptomatic carriers may have an even higher chance of getting the v***s in the future.
4) Unlike SARS and MARS where the immunity was a year or longer neutralizing antibodies in those that recovered C****-** start decreasing as quickly as six weeks.
5) A percentage of those that are asymptomatic have lung tissue damage. Of the 76 passengers on the Diamond Princess who were asymptomatic and had CT scans nearly half had lung tissue damage typical of c****av***s infection.
It appears the main difference between those that are asymptomatic and those that have symptoms are the results of the body fighting the disease i.e. fever and inflammation and NOT what the v***s is actually doing to the body. Another study showed that 66.7% of asymptomatic individuals had a******lities in one lung and 33.3% had a******lities in both lungs.
So now lets look at the Spanish flu
As many probably know there were several waves of the Spanish flu and that young adults and children were especially vulnerable. The first wave started in the United States in the March 1918 through July and then the second wave started in August 2018 with the most deadly month being October. The third and fourth wave was more isolated but the third wave was still more deadly than the first.
The thing to look at here is the first two waves:
First Wave: Deadly for those that were sick and elderly. Most adults that were affected had normal flu symptoms. Younger people were almost not affected.
Second Wave: Most that had the flu during the first wave were immune in the second phase. Those that were affected were primarily the young.
There are a lot of theories about how the v***s spread and why the second wave was so devastating to young people but all of the theories were based very limited understanding on v***ses in particular and even now our experts are somewhat baffled at the ability to be asymptomatic and have the disease.
For example, people thought that soldiers were a group that was especially vulnerable because of their environment but if you look at it through the lens of today you can make the case that they were because:
1) They are more than likely young adults
2) There was no limited social distancing
3) They were not immune in the second wave because they either weren't exposed to or they were asymptomatic during the first wave.
In conclusion we have limited understanding about the affects of a v***s on individuals who have no or limited immunity to the v***s because most of the v***ses that we are exposed too aren't new or different enough to for the bodies defence mechanisms to not identify and react.
Most importantly we don't know what affect the next wave will be on those that were asymptomatic in the first wave. We know there is a chance that their lungs will already have tissue damage and other possibly cardiovascular issues.
The second wave of the Spanish flu may have nothing to do with initial lack of symptoms in young people during the first wave but the similarities should be noted and reflect our decisions on how we talk to our young people about just how immune they are to C****-** and what decisions we make before there is a v*****e available.
Finally, the second wave of C****-** is almost a certainty because of the limited time frame of immunity shown in those that have recovered as well as the limited immunity if any of those that were asymptomatic initially. If this runs a similar course as the Spanish flu we will see infections (with symptoms) in younger, initially asymptomatic starting in as early as August or September. For those young people that were never initially infected they will get a pass until the next wave or hopefully there is a v*****e by then.
Reference link:
https://www.nature.com/articles/s41591-020-0965-6