V*****e That Completely Prevents Lethal Lassa Fever Infection
Oct 24, 2017 14:29:53 #
I believe this to be big news. So why are we not hearing anything about it?
PLYMOUTH MEETING, Pa., Oct. 24, 2017 (GLOBE NEWSWIRE) -- Inovio Pharmaceuticals, Inc. (NASDAQ:INO) today announced results of a study in which a DNA v*****e provided 100% protection for non-human primates challenged with a lethal dose of the Lassa fever v***s. Lassa is a virulent hemorrhagic v***s, similar to Ebola, which infects approximately 300,000 people annually. These results were published in the most recent issue of Human V*****es & Immunotherapeutics in an article entitled, “A DNA V*****e Delivered by Dermal Electroporation Fully Protects Cynomolgus Macaques Against Lassa Fever,” by Inovio researchers and U.S. Army collaborators.
In the study, funded by a previously awarded $3.5 million grant from the National Institute of Allergy and Infectious Diseases (NIAID), the animals first received Inovio’s DNA v*****e against Lassa hemorrhagic fever via intradermal administration with CELLECTRA® delivery device. The animals were then challenged with a lethal dose of the Lassa v***s. All of the animals survived; in fact, none of the v******ted animals displayed any signs of disease.
Dr. J. Joseph Kim, Inovio's President and Chief Executive Officer, said, “Inovio demonstrates our full commitment to global public health in this innovative public/private partnership against a virulent v***s with p******c and bioterror potential. Our DNA-based platform is especially well-suited to rapidly respond to v***l outbreaks and newly emerging pathogens due to its safety profile, ease and speed of development and manufacturing as well as the ability to be shipped and stored without a cold-chain environment. Inovio has shown these attributes most recently as the first organization to produce Zika and MERS v*****es and the first to report positive human data from these v*****e trials. Inovio will continue to lead in the global efforts to protect the world from multiple epidemic threats.”
Inovio is collaborating with Dr. Connie Schmaljohn, Chief Scientist at the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) and her group. The goal of this public/private partnership is to develop v*****es that would facilitate rapid v******tion of U.S. troops stationed around the world against multiple deadly infectious diseases and protect civilian populations from p******c and bioterror threats.
Lassa fever is an acute disease that annually infects up to 300,000 people, mostly in Central and West Africa regions. The disease can cause fever and hemorrhaging of various parts of the body -- including the eyes and nose -- and can be spread through contact with an infected rat. Person to person t***smission is also possible, albeit less common. Immediate deaths from the infection are approximately 5,000 per year, but based on serologic surveys the estimated fatality rate is more than 50% of Lassa infected people because the infection can persist for at least one year after infection.
Because of rapid and wide global travel and commerce, Lassa is not only a major health threat in Africa, but throughout the world. Lassa v***s has been classified as a Category A biological threat agent by the U.S. Centers for Disease Control and Prevention. Along with MERS and Nipah, Lassa v***s has been selected as the top potential global epidemic targets for new v*****e development by the newly-formed multi-billion dollar, Coalition for Epidemic Preparedness Initiative (CEPI) in 2017.
While the country is embroiled in politics, this company is ever moving onward.
In a time where stagnation of the human race has caused a near a stand still. It is good to see there are still people that are working for our future.
RETW
PLYMOUTH MEETING, Pa., Oct. 24, 2017 (GLOBE NEWSWIRE) -- Inovio Pharmaceuticals, Inc. (NASDAQ:INO) today announced results of a study in which a DNA v*****e provided 100% protection for non-human primates challenged with a lethal dose of the Lassa fever v***s. Lassa is a virulent hemorrhagic v***s, similar to Ebola, which infects approximately 300,000 people annually. These results were published in the most recent issue of Human V*****es & Immunotherapeutics in an article entitled, “A DNA V*****e Delivered by Dermal Electroporation Fully Protects Cynomolgus Macaques Against Lassa Fever,” by Inovio researchers and U.S. Army collaborators.
In the study, funded by a previously awarded $3.5 million grant from the National Institute of Allergy and Infectious Diseases (NIAID), the animals first received Inovio’s DNA v*****e against Lassa hemorrhagic fever via intradermal administration with CELLECTRA® delivery device. The animals were then challenged with a lethal dose of the Lassa v***s. All of the animals survived; in fact, none of the v******ted animals displayed any signs of disease.
Dr. J. Joseph Kim, Inovio's President and Chief Executive Officer, said, “Inovio demonstrates our full commitment to global public health in this innovative public/private partnership against a virulent v***s with p******c and bioterror potential. Our DNA-based platform is especially well-suited to rapidly respond to v***l outbreaks and newly emerging pathogens due to its safety profile, ease and speed of development and manufacturing as well as the ability to be shipped and stored without a cold-chain environment. Inovio has shown these attributes most recently as the first organization to produce Zika and MERS v*****es and the first to report positive human data from these v*****e trials. Inovio will continue to lead in the global efforts to protect the world from multiple epidemic threats.”
Inovio is collaborating with Dr. Connie Schmaljohn, Chief Scientist at the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) and her group. The goal of this public/private partnership is to develop v*****es that would facilitate rapid v******tion of U.S. troops stationed around the world against multiple deadly infectious diseases and protect civilian populations from p******c and bioterror threats.
Lassa fever is an acute disease that annually infects up to 300,000 people, mostly in Central and West Africa regions. The disease can cause fever and hemorrhaging of various parts of the body -- including the eyes and nose -- and can be spread through contact with an infected rat. Person to person t***smission is also possible, albeit less common. Immediate deaths from the infection are approximately 5,000 per year, but based on serologic surveys the estimated fatality rate is more than 50% of Lassa infected people because the infection can persist for at least one year after infection.
Because of rapid and wide global travel and commerce, Lassa is not only a major health threat in Africa, but throughout the world. Lassa v***s has been classified as a Category A biological threat agent by the U.S. Centers for Disease Control and Prevention. Along with MERS and Nipah, Lassa v***s has been selected as the top potential global epidemic targets for new v*****e development by the newly-formed multi-billion dollar, Coalition for Epidemic Preparedness Initiative (CEPI) in 2017.
While the country is embroiled in politics, this company is ever moving onward.
In a time where stagnation of the human race has caused a near a stand still. It is good to see there are still people that are working for our future.
RETW
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